Formulas of lab animal diets must contain a variety of raw materials and be scientifically proportioned according to the nutritional needs of lab animals. For the verified formulas, the long-term fixed production shall be maintained.
Lab animals are prone to anorexia when they eat purified high-fat diets, in fact, this is a normal phenomenon in the process of feeding. High-fat diet contains more calories than standard diet, so lab animals are more likely to feel full.
The phenotype of SPF mice in high Saa + Ade diet group was similar to that of germ-free mice, which indicated that low Saa + Ade diet aggravated the phenotype of chronic kidney disease, and the intestinal flora further amplified these effects.
There are two different classification methods for laboratory animal feed. The first one can be divided into cereal feed (grain-based feed), purified feed and chemically defined feed according to the composition of raw materials.
Some researchers fed germ-free KM mice with irradiated AIN-93G diet, resulting in emaciation, prominent spine protrusion and dirty hair, while on the vitamin adjusted AIN-93G diet, the growth and reproduction of germ-free KM mice were normal.
Compared with the purified feed, the cereal feed is mainly composed of grains. The composition of each raw material of cereal feed is very complex, there are more than one nutrient, and it is often difficult to separate,